Expression of Scavenger Receptors in Glial Cells
نویسندگان
چکیده
منابع مشابه
NMDA Receptors in Glial Cells: Pending Questions
Glutamate receptors of the N-methyl-D-aspartate (NMDA) type are involved in many cognitive processes, including behavior, learning and synaptic plasticity. For a long time NMDA receptors were thought to be the privileged domain of neurons; however, discoveries of the last 25 years have demonstrated their active role in glial cells as well. Despite the large number of studies in the field, there...
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Astrocytes and microglia associate to amyloid plaques, a pathological hallmark of Alzheimer disease. Microglia are activated by and can phagocytose -amyloid (A ). Scavenger receptors (SRs) are among the receptors mediating the uptake of fibrillar A in vitro. However, little is known about the function of the astrocytes surrounding the plaques or the nature of their interaction with A . It is un...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2005
ISSN: 0021-9258
DOI: 10.1074/jbc.m414686200